ctcRbase

Entry Detail

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General Information

Database ID: BRCA24038 Cancer Type: breast cancer Dataset: GSE55807 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: ICK Full Name: intestinal cell kinase Category: mRNA Synonyms: ECO|EJM10|LCK2|MRK Chromosome: chr6 Strand: - Coordinate: Start Site(bp): 53001279 End Site(bp): 53061802 Gene Summary: Eukaryotic protein kinases are enzymes that belong to a very extensive family of proteins which share a conserved catalytic core common with both serine/threonine and tyrosine protein kinases. This gene encodes an intestinal serine/threonine kinase harboring a dual phosphorylation site found in mitogen-activating protein (MAP) kinases. The protein localizes to the intestinal crypt region and is thought to be important in intestinal epithelial cell proliferation and differentiation. Alternative splicing has been observed at this locus and two variants, encoding the same isoform, have been identified. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000112144 HGNC ID: HGNC:21219 Entrez Gene: 22858

Expression Profile of ICK Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-let-7a-5p YES NO YES hsa-let-7b-5p YES NO YES hsa-let-7c-5p YES NO YES hsa-let-7d-5p YES NO YES hsa-let-7e-5p YES NO YES hsa-let-7f-5p YES NO YES hsa-let-7g-5p YES NO YES hsa-let-7i-5p YES NO YES hsa-miR-101-3p YES YES YES hsa-miR-10a-5p YES YES NO hsa-miR-10b-5p YES YES NO hsa-miR-128-3p YES YES NO hsa-miR-1297 YES YES NO hsa-miR-133a-3p YES NO YES hsa-miR-133b YES NO YES hsa-miR-134-5p YES YES NO hsa-miR-136-5p YES YES NO hsa-miR-139-5p YES YES YES hsa-miR-140-5p YES YES NO hsa-miR-142-5p YES NO YES hsa-miR-144-3p YES YES YES hsa-miR-153-3p YES YES NO hsa-miR-186-5p YES YES YES hsa-miR-197-3p YES YES NO hsa-miR-200b-3p YES YES YES hsa-miR-200c-3p YES YES YES hsa-miR-217 YES YES NO hsa-miR-218-5p YES YES YES hsa-miR-23a-3p YES YES NO hsa-miR-23b-3p YES YES NO hsa-miR-25-3p YES YES YES hsa-miR-26a-5p YES YES NO hsa-miR-26b-5p YES YES NO hsa-miR-300 YES NO YES hsa-miR-30a-5p YES YES YES hsa-miR-30b-5p YES YES YES hsa-miR-30c-5p YES YES YES hsa-miR-30d-5p YES YES YES hsa-miR-30e-5p YES YES YES hsa-miR-31-5p YES YES NO hsa-miR-32-5p YES YES YES hsa-miR-340-5p YES YES NO hsa-miR-363-3p YES YES YES hsa-miR-367-3p YES YES YES hsa-miR-369-3p YES NO NO hsa-miR-374a-5p YES YES NO hsa-miR-374b-5p YES YES NO hsa-miR-377-3p YES YES NO hsa-miR-381-3p YES NO YES hsa-miR-382-5p YES NO YES hsa-miR-383-5p YES YES NO hsa-miR-410-3p YES NO NO hsa-miR-425-5p YES YES NO hsa-miR-429 YES YES YES hsa-miR-431-5p YES YES NO hsa-miR-448 YES YES YES hsa-miR-543 YES YES YES hsa-miR-655-3p YES NO YES hsa-miR-92a-3p YES YES YES hsa-miR-92b-3p YES YES YES hsa-miR-98-5p YES NO YES Display: