| ncRNA Symbol: | ITPR3 | | Full Name: | inositol 1,4,5-trisphosphate receptor type 3 | | Category: | mRNA | | Synonyms: | IP3R|IP3R3 | | Chromosome: | chr6 | | Strand: | + | | Coordinate: | | Start Site(bp): | 33620365 | End Site(bp): | 33696574 | | | Gene Summary: | This gene encodes a receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium. The receptor contains a calcium channel at the C-terminus and the ligand-binding site at the N-terminus. Knockout studies in mice suggest that type 2 and type 3 inositol 1,4,5-trisphosphate receptors play a key role in exocrine secretion underlying energy metabolism and growth. [provided by RefSeq, Aug 2010] | | External Links: | |
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