| ncRNA Symbol: | PEX6 |
| Full Name: | peroxisomal biogenesis factor 6 |
| Category: | mRNA |
| Synonyms: | HMLR2|PAF-2|PAF2|PBD4A|PDB4B|PXAAA1 |
| Chromosome: | chr6 |
| Strand: | - |
| Coordinate: | | Start Site(bp): | 42963870 | End Site(bp): | 42979220 |
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| Gene Summary: | This gene encodes a member of the AAA (ATPases associated with diverse cellular activities) family of ATPases. This member is a predominantly cytoplasmic protein, which plays a direct role in peroxisomal protein import and is required for PTS1 (peroxisomal targeting signal 1, a C-terminal tripeptide of the sequence ser-lys-leu) receptor activity. Mutations in this gene cause peroxisome biogenesis disorders of complementation group 4 and complementation group 6. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015] |
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