ctcRbase

Entry Detail

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General Information

Database ID: BRCA26131 Cancer Type: breast cancer Dataset: GSE55807 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: KRAS Full Name: KRAS proto-oncogene, GTPase Category: mRNA Synonyms: C-K-RAS|CFC2|K-RAS2A|K-RAS2B|K-RAS4A|K-RAS4B|K-Ras|KI-RAS|KRAS1|KRAS2|NS|NS3|RALD|RASK2|c-Ki-ras2 Chromosome: chr12 Strand: - Coordinate: Start Site(bp): 25204789 End Site(bp): 25250936 Gene Summary: This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000133703 HGNC ID: HGNC:6407 Entrez Gene: 3845

Expression Profile of KRAS Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-1271-5p YES YES YES hsa-miR-132-3p YES YES NO hsa-miR-134-5p YES NO YES hsa-miR-1-3p YES YES YES hsa-miR-143-3p YES YES YES hsa-miR-155-5p YES YES YES hsa-miR-15a-5p YES NO YES hsa-miR-15b-5p YES NO YES hsa-miR-16-5p YES NO YES hsa-miR-181a-5p YES YES NO hsa-miR-181b-5p YES YES NO hsa-miR-181c-5p YES YES NO hsa-miR-181d-5p YES YES NO hsa-miR-193a-3p YES NO YES hsa-miR-193b-3p YES NO YES hsa-miR-195-5p YES NO YES hsa-miR-199a-5p YES YES NO hsa-miR-199b-5p YES YES NO hsa-miR-19a-3p YES NO YES hsa-miR-19b-3p YES NO YES hsa-miR-200b-3p YES NO YES hsa-miR-200c-3p YES NO YES hsa-miR-204-5p YES YES NO hsa-miR-206 YES YES YES hsa-miR-211-5p YES YES NO hsa-miR-212-3p YES YES NO hsa-miR-214-3p YES NO NO hsa-miR-216a-5p YES NO YES hsa-miR-216b-5p YES YES YES hsa-miR-217 YES NO YES hsa-miR-27a-3p YES NO YES hsa-miR-27b-3p YES NO YES hsa-miR-300 YES NO YES hsa-miR-30a-5p YES YES YES hsa-miR-30b-5p YES YES YES hsa-miR-30c-5p YES YES YES hsa-miR-30d-5p YES YES YES hsa-miR-30e-5p YES YES YES hsa-miR-323a-3p YES NO YES hsa-miR-326 YES YES NO hsa-miR-329-3p YES YES NO hsa-miR-330-5p YES YES NO hsa-miR-362-3p YES YES NO hsa-miR-374a-5p YES YES NO hsa-miR-374b-5p YES YES NO hsa-miR-376c-3p YES YES NO hsa-miR-381-3p YES NO YES hsa-miR-383-5p YES YES NO hsa-miR-384 YES YES NO hsa-miR-421 YES NO YES hsa-miR-424-5p YES NO YES hsa-miR-429 YES NO YES hsa-miR-433-3p YES NO YES hsa-miR-448 YES NO YES hsa-miR-497-5p YES NO YES hsa-miR-501-3p YES NO YES hsa-miR-502-3p YES NO YES hsa-miR-532-5p YES NO YES hsa-miR-543 YES YES NO hsa-miR-582-5p YES NO YES hsa-miR-613 YES YES YES hsa-miR-873-5p YES YES NO hsa-miR-877-5p YES NO YES hsa-miR-96-5p YES YES YES Display: