ctcRbase

Entry Detail

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General Information

Database ID: BRCA27934 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: WNT5A Full Name: Wnt family member 5A Category: mRNA Synonyms: hWNT5A Chromosome: chr3 Strand: - Coordinate: Start Site(bp): 55465715 End Site(bp): 55490539 Gene Summary: The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene encodes a member of the WNT family that signals through both the canonical and non-canonical WNT pathways. This protein is a ligand for the seven transmembrane receptor frizzled-5 and the tyrosine kinase orphan receptor 2. This protein plays an essential role in regulating developmental pathways during embryogenesis. This protein may also play a role in oncogenesis. Mutations in this gene are the cause of autosomal dominant Robinow syndrome. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012] External Links: Ensembl ID: ENSG00000114251 HGNC ID: HGNC:12784 Entrez Gene: 7474

Expression Profile of WNT5A Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-1271-5p YES YES NO hsa-miR-129-5p YES YES NO hsa-miR-1297 YES YES YES hsa-miR-136-5p YES YES NO hsa-miR-141-3p YES YES YES hsa-miR-155-5p YES YES NO hsa-miR-183-5p YES YES NO hsa-miR-186-5p YES YES NO hsa-miR-194-5p YES YES NO hsa-miR-197-3p YES YES NO hsa-miR-200a-3p YES YES YES hsa-miR-200b-3p YES YES NO hsa-miR-200c-3p YES YES NO hsa-miR-217 YES YES NO hsa-miR-26a-5p YES YES YES hsa-miR-26b-5p YES YES YES hsa-miR-300 YES YES YES hsa-miR-365a-3p YES YES YES hsa-miR-374a-5p YES YES YES hsa-miR-374b-5p YES YES YES hsa-miR-376c-3p YES YES NO hsa-miR-381-3p YES YES YES hsa-miR-421 YES YES NO hsa-miR-429 YES YES NO hsa-miR-448 YES YES NO hsa-miR-876-5p YES YES NO Display: