| ncRNA Symbol: | FENDRR |
| Full Name: | FOXF1 adjacent non-coding developmental regulatory RNA |
| Category: | lncRNA |
| Synonyms: | FOXF1-AS1|FOXF1AS1|TCONS_00024240|lincFOXF1|onco-lncRNA-21 |
| Chromosome: | chr16 |
| Strand: | - |
| Coordinate: | | Start Site(bp): | 86474529 | End Site(bp): | 86509099 |
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| Gene Summary: | This gene produces a spliced long non-coding RNA transcribed bidirectionally with FOXF1 on the opposite strand. A similar gene in mouse is essential for normal development of the heart and body wall. The encoded transcript is thought to act by binding to polycomb repressive complex 2 (PRC2) and/or TrxG/MLL complexes to promote the methylation of the promoters of target genes, thus reducing their expression. It has been suggested that this transcript may play a role in the progression of gastric cancer. Alternatively spliced transcript variants have been identified. [provided by RefSeq, Mar 2015] |
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