ctcRbase

Entry Detail

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General Information

Database ID: PAAD01198 Cancer Type: pancreatic cancer Dataset: GSE60407 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: HIF1A Full Name: hypoxia inducible factor 1 subunit alpha Category: mRNA Synonyms: HIF-1-alpha|HIF-1A|HIF-1alpha|HIF1|HIF1-ALPHA|MOP1|PASD8|bHLHe78 Chromosome: chr14 Strand: + Coordinate: Start Site(bp): 61695513 End Site(bp): 61748259 Gene Summary: This gene encodes the alpha subunit of transcription factor hypoxia-inducible factor-1 (HIF-1), which is a heterodimer composed of an alpha and a beta subunit. HIF-1 functions as a master regulator of cellular and systemic homeostatic response to hypoxia by activating transcription of many genes, including those involved in energy metabolism, angiogenesis, apoptosis, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. HIF-1 thus plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2011] External Links: Ensembl ID: ENSG00000100644 HGNC ID: HGNC:4910 Entrez Gene: 3091

Expression Profile of HIF1A Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-106a-5p YES YES YES hsa-miR-106b-5p YES YES YES hsa-miR-10a-5p YES YES NO hsa-miR-10b-5p YES YES NO hsa-miR-1271-5p YES YES NO hsa-miR-130a-3p YES YES NO hsa-miR-130b-3p YES YES NO hsa-miR-135a-5p YES YES YES hsa-miR-135b-5p YES YES YES hsa-miR-138-5p YES YES YES hsa-miR-1-3p YES YES NO hsa-miR-151a-3p YES NO YES hsa-miR-153-3p YES YES NO hsa-miR-155-5p YES YES YES hsa-miR-17-5p YES YES YES hsa-miR-182-5p YES YES NO hsa-miR-186-5p YES YES YES hsa-miR-18a-5p YES YES NO hsa-miR-18b-5p YES YES NO hsa-miR-194-5p YES YES YES hsa-miR-199a-5p YES YES YES hsa-miR-199b-5p YES YES YES hsa-miR-19a-3p YES YES YES hsa-miR-19b-3p YES YES YES hsa-miR-206 YES YES NO hsa-miR-20a-5p YES YES YES hsa-miR-20b-5p YES YES YES hsa-miR-217 YES YES YES hsa-miR-28-5p YES YES NO hsa-miR-301a-3p YES YES NO hsa-miR-301b-3p YES YES NO hsa-miR-302a-3p YES YES NO hsa-miR-302b-3p YES YES NO hsa-miR-302c-3p YES YES NO hsa-miR-302d-3p YES YES NO hsa-miR-302e YES YES NO hsa-miR-320a YES YES NO hsa-miR-320b YES YES NO hsa-miR-320c YES YES NO hsa-miR-320d YES YES NO hsa-miR-330-3p YES NO YES hsa-miR-338-3p YES YES NO hsa-miR-33a-5p YES YES NO hsa-miR-33b-5p YES YES NO hsa-miR-340-5p YES YES YES hsa-miR-346 YES YES NO hsa-miR-361-5p YES YES NO hsa-miR-365a-3p YES YES NO hsa-miR-371a-5p YES YES NO hsa-miR-372-3p YES YES NO hsa-miR-373-3p YES YES NO hsa-miR-376a-3p YES YES YES hsa-miR-376b-3p YES YES YES hsa-miR-376c-3p YES YES NO hsa-miR-384 YES YES NO hsa-miR-410-3p YES YES NO hsa-miR-411-5p YES YES NO hsa-miR-433-3p YES YES YES hsa-miR-448 YES YES NO hsa-miR-454-3p YES YES NO hsa-miR-488-3p YES YES YES hsa-miR-494-3p YES YES YES hsa-miR-495-3p YES NO YES hsa-miR-519d-3p YES YES YES hsa-miR-520a-3p YES YES NO hsa-miR-520b YES YES NO hsa-miR-520c-3p YES YES NO hsa-miR-520d-3p YES YES NO hsa-miR-520e YES YES NO hsa-miR-542-3p YES YES YES hsa-miR-543 YES YES NO hsa-miR-582-5p YES NO YES hsa-miR-613 YES YES NO hsa-miR-93-5p YES YES YES hsa-miR-96-5p YES YES NO Display: