Entry Detail



General Information

Database ID:PAAD03965
Cancer Type:pancreatic cancer
Dataset:GSE60407
CTCs/CTM Isolation Method:CTC-iChip



Gene Information

ncRNA Symbol:ARHGAP42
Full Name:Rho GTPase activating protein 42
Category:mRNA
Synonyms:AD031|GRAF3|TMEM133
Chromosome:chr11
Strand:+
Coordinate:
Start Site(bp):100687653End Site(bp):100991937
Gene Summary:This gene encodes a Rho GTPase-activating protein (RhoGAP), and member of the GRAF or BAR-PH family of proteins. Expression of this gene is enriched in vascular smooth muscle cells and the encoded protein inhibits RhoA activity to regulate vascular tone and control blood pressure. A mutation in the first intron of this gene modulates its expression and is associated with reduced blood pressure in human patients with borderline hypertension. [provided by RefSeq, Jul 2017]
External Links:
Ensembl ID:ENSG00000165895
HGNC ID:HGNC:26545
Entrez Gene:143872



Expression Profile of ARHGAP42 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-101-3p
YES
YES
NO
hsa-miR-106a-5p
YES
YES
YES
hsa-miR-106b-5p
YES
YES
YES
hsa-miR-130a-3p
YES
YES
NO
hsa-miR-130b-3p
YES
YES
NO
hsa-miR-138-5p
NO
YES
YES
hsa-miR-139-5p
YES
YES
NO
hsa-miR-141-3p
YES
YES
NO
hsa-miR-144-3p
YES
YES
NO
hsa-miR-154-5p
YES
YES
YES
hsa-miR-17-5p
YES
YES
YES
hsa-miR-186-5p
NO
YES
YES
hsa-miR-200a-3p
YES
YES
NO
hsa-miR-20a-5p
YES
YES
YES
hsa-miR-20b-5p
YES
YES
YES
hsa-miR-221-3p
NO
YES
YES
hsa-miR-222-3p
NO
YES
YES
hsa-miR-301a-3p
YES
YES
NO
hsa-miR-301b-3p
YES
YES
NO
hsa-miR-371a-5p
YES
YES
NO
hsa-miR-454-3p
YES
YES
NO
hsa-miR-519d-3p
YES
YES
YES
hsa-miR-93-5p
YES
YES
YES
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