ctcRbase

Entry Detail

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General Information

Database ID: PAAD04431 Cancer Type: pancreatic cancer Dataset: GSE60407 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: SPTBN4 Full Name: spectrin beta, non-erythrocytic 4 Category: mRNA Synonyms: CMND|NEDHND|QV|SPNB4|SPTBN3 Chromosome: chr19 Strand: + Coordinate: Start Site(bp): 40466241 End Site(bp): 40576464 Gene Summary: Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is composed of two antiparallel dimers of alpha- and beta- subunits. This gene is one member of a family of beta-spectrin genes. The encoded protein localizes to the nuclear matrix, PML nuclear bodies, and cytoplasmic vesicles. A highly similar gene in the mouse is required for localization of specific membrane proteins in polarized regions of neurons. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000160460 HGNC ID: HGNC:14896 Entrez Gene: 57731

Expression Profile of SPTBN4 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-let-7a-5p YES NO YES hsa-let-7b-5p YES NO YES hsa-let-7c-5p YES NO YES hsa-let-7d-5p YES NO YES hsa-let-7e-5p YES NO YES hsa-let-7f-5p YES NO YES hsa-let-7g-5p YES NO YES hsa-let-7i-5p YES NO YES hsa-miR-103a-3p YES YES YES hsa-miR-107 YES YES YES hsa-miR-760 YES NO YES hsa-miR-98-5p YES NO YES Display: