ctcRbase

Entry Detail

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General Information

Database ID: PRAD07101 Cancer Type: prostate cancer Dataset: GSE104209 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: XPC Full Name: XPC complex subunit, DNA damage recognition and repair factor Category: mRNA Synonyms: RAD4|XP3|XPCC|p125 Chromosome: chr3 Strand: - Coordinate: Start Site(bp): 14145147 End Site(bp): 14178783 Gene Summary: The protein encoded by this gene is a key component of the XPC complex, which plays an important role in the early steps of global genome nucleotide excision repair (NER). The encoded protein is important for damage sensing and DNA binding, and shows a preference for single-stranded DNA. Mutations in this gene or some other NER components can result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2017] External Links: Ensembl ID: ENSG00000154767 HGNC ID: HGNC:12816 Entrez Gene: 7508

Expression Profile of XPC Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-103a-3p YES NO NO hsa-miR-107 YES NO NO hsa-miR-141-3p YES YES NO hsa-miR-197-3p YES YES NO hsa-miR-200a-3p YES YES NO hsa-miR-224-5p YES YES NO hsa-miR-371a-5p YES YES NO hsa-miR-486-5p YES YES NO hsa-miR-9-5p YES YES NO Display: