ctcRbase

Entry Detail

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General Information

Database ID: PRAD07368 Cancer Type: prostate cancer Dataset: GSE104209 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: SPRTN Full Name: SprT-like N-terminal domain Category: mRNA Synonyms: C1orf124|DVC1|PRO4323|spartan Chromosome: chr1 Strand: + Coordinate: Start Site(bp): 231337104 End Site(bp): 231355023 Gene Summary: The protein encoded by this gene may play a role in DNA repair during replication of damaged DNA. This protein recruits valosin containing protein (p97) to stalled DNA replication forks where it may prevent excessive translesional DNA synthesis and limit the number of DNA-damage induced mutations. It may also be involved in replication-related G2/M-checkpoint regulation. Deficiency of a similar protein in mouse causes chromosomal instability and progeroid phenotypes. Mutations in this gene have been associated with Ruijs-Aalfs syndrome (RJALS). Alternatively spliced transcript variants have been identified. [provided by RefSeq, Mar 2015] External Links: Ensembl ID: ENSG00000010072 HGNC ID: HGNC:25356 Entrez Gene: 83932

Expression Profile of SPRTN Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-124-3p YES YES YES hsa-miR-125a-5p YES YES NO hsa-miR-125b-5p YES YES NO hsa-miR-129-5p YES YES NO hsa-miR-132-3p YES YES NO hsa-miR-1-3p YES YES NO hsa-miR-144-3p YES YES NO hsa-miR-146a-5p YES YES NO hsa-miR-146b-5p YES YES NO hsa-miR-182-5p YES YES YES hsa-miR-200b-3p YES YES NO hsa-miR-200c-3p YES YES NO hsa-miR-206 YES YES NO hsa-miR-212-3p YES YES NO hsa-miR-300 YES YES NO hsa-miR-302a-3p YES YES YES hsa-miR-302b-3p YES YES YES hsa-miR-302c-3p YES YES YES hsa-miR-302d-3p YES YES YES hsa-miR-302e YES YES YES hsa-miR-31-5p YES YES NO hsa-miR-361-5p YES YES NO hsa-miR-372-3p YES YES YES hsa-miR-373-3p YES YES YES hsa-miR-374a-5p YES YES NO hsa-miR-374b-5p YES YES NO hsa-miR-381-3p YES YES NO hsa-miR-410-3p YES YES NO hsa-miR-429 YES YES NO hsa-miR-455-3p YES NO YES hsa-miR-490-3p YES YES NO hsa-miR-505-3p YES YES NO hsa-miR-506-3p YES NO YES hsa-miR-520a-3p YES YES YES hsa-miR-520b YES YES YES hsa-miR-520c-3p YES YES YES hsa-miR-520d-3p YES YES YES hsa-miR-520e YES YES YES hsa-miR-613 YES YES NO hsa-miR-9-5p YES YES NO Display: