ctcRbase

Entry Detail

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General Information

Database ID: PRAD07772 Cancer Type: prostate cancer Dataset: GSE104209 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: PPM1B Full Name: protein phosphatase, Mg2+/Mn2+ dependent 1B Category: mRNA Synonyms: PP2C-beta|PP2C-beta-X|PP2CB|PP2CBETA|PPC2BETAX Chromosome: chr2 Strand: + Coordinate: Start Site(bp): 44167969 End Site(bp): 44244384 Gene Summary: The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase has been shown to dephosphorylate cyclin-dependent kinases (CDKs), and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to cause cell-growth arrest or cell death. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional transcript variants have been described, but currently do not represent full-length sequences. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000138032 HGNC ID: HGNC:9276 Entrez Gene: 5495

Expression Profile of PPM1B Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-128-3p YES YES NO hsa-miR-1297 YES YES NO hsa-miR-132-3p YES YES NO hsa-miR-135a-5p YES YES NO hsa-miR-135b-5p YES YES NO hsa-miR-139-5p YES YES NO hsa-miR-141-3p YES YES NO hsa-miR-143-3p YES NO YES hsa-miR-146a-5p YES YES NO hsa-miR-146b-5p YES YES NO hsa-miR-153-3p YES YES NO hsa-miR-154-5p YES YES NO hsa-miR-182-5p YES YES NO hsa-miR-186-5p YES YES YES hsa-miR-18a-5p YES YES NO hsa-miR-18b-5p YES YES NO hsa-miR-199a-3p YES NO YES hsa-miR-199a-5p YES YES YES hsa-miR-199b-3p YES NO YES hsa-miR-199b-5p YES YES YES hsa-miR-200a-3p YES YES NO hsa-miR-200b-3p YES YES YES hsa-miR-200c-3p YES YES YES hsa-miR-212-3p YES YES NO hsa-miR-216a-5p YES YES NO hsa-miR-216b-5p YES YES NO hsa-miR-217 YES YES NO hsa-miR-26a-5p YES YES NO hsa-miR-26b-5p YES YES NO hsa-miR-27a-3p YES YES NO hsa-miR-27b-3p YES YES NO hsa-miR-296-3p YES YES NO hsa-miR-320a YES YES NO hsa-miR-320b YES YES NO hsa-miR-320c YES YES NO hsa-miR-320d YES YES NO hsa-miR-329-3p YES YES NO hsa-miR-330-3p YES NO YES hsa-miR-338-3p YES YES NO hsa-miR-33a-5p YES YES NO hsa-miR-33b-5p YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-362-3p YES YES NO hsa-miR-374a-5p YES YES NO hsa-miR-374b-5p YES YES NO hsa-miR-376c-3p YES YES NO hsa-miR-377-3p YES YES NO hsa-miR-382-5p YES YES NO hsa-miR-383-5p YES YES NO hsa-miR-384 YES YES NO hsa-miR-410-3p YES YES NO hsa-miR-411-5p YES YES NO hsa-miR-421 YES YES NO hsa-miR-429 YES YES YES hsa-miR-448 YES YES NO hsa-miR-487a-3p YES NO YES hsa-miR-488-3p YES YES NO hsa-miR-494-3p YES YES YES hsa-miR-495-3p YES YES NO hsa-miR-758-3p YES YES NO Display: