ctcRbase

Entry Detail

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General Information

Database ID: PRAD08022 Cancer Type: prostate cancer Dataset: GSE104209 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: GRK3 Full Name: G protein-coupled receptor kinase 3 Category: mRNA Synonyms: ADRBK2|BARK2 Chromosome: chr22 Strand: + Coordinate: Start Site(bp): 25564849 End Site(bp): 25729294 Gene Summary: The beta-adrenergic receptor kinase specifically phosphorylates the agonist-occupied form of the beta-adrenergic and related G protein-coupled receptors. Overall, the beta adrenergic receptor kinase 2 has 85% amino acid similarity with beta adrenergic receptor kinase 1, with the protein kinase catalytic domain having 95% similarity. These data suggest the existence of a family of receptor kinases which may serve broadly to regulate receptor function. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000100077 HGNC ID: HGNC:290 Entrez Gene: 157

Expression Profile of GRK3 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-let-7a-5p YES NO YES hsa-let-7b-5p YES NO YES hsa-let-7c-5p YES NO YES hsa-let-7d-5p YES NO YES hsa-let-7e-5p YES NO YES hsa-let-7f-5p YES NO YES hsa-let-7g-5p YES NO YES hsa-let-7i-5p YES NO YES hsa-miR-1197 YES NO YES hsa-miR-136-5p YES NO YES hsa-miR-1-3p YES YES YES hsa-miR-199a-3p YES NO YES hsa-miR-199b-3p YES NO YES hsa-miR-206 YES YES YES hsa-miR-218-5p YES NO YES hsa-miR-338-3p YES NO YES hsa-miR-421 YES YES NO hsa-miR-495-3p YES YES YES hsa-miR-613 YES YES YES hsa-miR-98-5p YES NO YES Display: