ctcRbase

Entry Detail

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General Information

Database ID: PRAD08459 Cancer Type: prostate cancer Dataset: GSE104209 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: PHF8 Full Name: PHD finger protein 8 Category: mRNA Synonyms: JHDM1F|KDM7B|MRXSSD|ZNF422 Chromosome: chrX Strand: - Coordinate: Start Site(bp): 53936676 End Site(bp): 54048958 Gene Summary: The protein encoded by this gene is a histone lysine demethylase that preferentially acts on histones in the monomethyl or dimethyl states. The encoded protein requires Fe(2+) ion, 2-oxoglutarate, and oxygen for its catalytic activity. The protein has an N-terminal PHD finger and a central Jumonji C domain. This gene is thought to function as a transcription activator. Defects in this gene are a cause of syndromic X-linked Siderius type intellectual disability (MRXSSD) and over-expression of this gene is associated with several forms of cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2017] External Links: Ensembl ID: ENSG00000172943 HGNC ID: HGNC:20672 Entrez Gene: 23133

Expression Profile of PHF8 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-let-7a-5p YES NO YES hsa-let-7b-5p YES NO YES hsa-let-7c-5p YES NO YES hsa-let-7d-5p YES NO YES hsa-let-7e-5p YES NO YES hsa-let-7f-5p YES NO YES hsa-let-7g-5p YES NO YES hsa-let-7i-5p YES NO YES hsa-miR-129-5p YES YES YES hsa-miR-130a-3p YES YES NO hsa-miR-130b-3p YES YES NO hsa-miR-134-5p YES NO YES hsa-miR-140-5p YES YES NO hsa-miR-150-5p YES YES NO hsa-miR-182-5p YES YES YES hsa-miR-18a-5p YES YES NO hsa-miR-18b-5p YES YES NO hsa-miR-194-5p YES YES NO hsa-miR-205-5p YES YES NO hsa-miR-22-3p YES YES YES hsa-miR-24-3p YES YES NO hsa-miR-28-3p YES NO YES hsa-miR-301a-3p YES YES NO hsa-miR-301b-3p YES YES NO hsa-miR-31-5p YES YES YES hsa-miR-320a YES YES YES hsa-miR-320b YES YES YES hsa-miR-320c YES YES YES hsa-miR-320d YES YES YES hsa-miR-323a-3p YES NO YES hsa-miR-331-3p YES NO YES hsa-miR-340-5p YES NO YES hsa-miR-423-5p YES NO NO hsa-miR-454-3p YES YES NO hsa-miR-485-5p YES YES NO hsa-miR-488-3p YES NO YES hsa-miR-491-5p YES YES NO hsa-miR-494-3p YES YES YES hsa-miR-495-3p YES NO YES hsa-miR-665 YES NO YES hsa-miR-875-5p YES YES NO hsa-miR-9-5p YES NO YES hsa-miR-98-5p YES NO YES Display: