ctcRbase

Entry Detail

---



General Information

Database ID: PRAD08747 Cancer Type: prostate cancer Dataset: GSE104209 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: APPL1 Full Name: adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 Category: mRNA Synonyms: APPL|DIP13alpha|MODY14 Chromosome: chr3 Strand: + Coordinate: Start Site(bp): 57227737 End Site(bp): 57273468 Gene Summary: The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000157500 HGNC ID: HGNC:24035 Entrez Gene: 26060

Expression Profile of APPL1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES NO YES hsa-miR-103a-3p YES NO YES hsa-miR-106a-5p YES NO YES hsa-miR-106b-5p YES NO YES hsa-miR-107 YES NO YES hsa-miR-125a-5p YES YES NO hsa-miR-125b-5p YES YES NO hsa-miR-1271-5p YES YES YES hsa-miR-130a-3p YES YES YES hsa-miR-130b-3p YES YES YES hsa-miR-142-5p YES NO YES hsa-miR-143-3p YES YES NO hsa-miR-145-5p YES YES YES hsa-miR-146a-5p YES YES YES hsa-miR-146b-5p YES YES YES hsa-miR-17-5p YES NO YES hsa-miR-182-5p YES YES YES hsa-miR-192-5p YES YES NO hsa-miR-194-5p YES YES NO hsa-miR-19a-3p YES YES YES hsa-miR-19b-3p YES YES YES hsa-miR-200b-3p YES YES NO hsa-miR-200c-3p YES YES NO hsa-miR-20a-5p YES NO YES hsa-miR-20b-5p YES NO YES hsa-miR-215-5p YES YES NO hsa-miR-216a-5p YES YES YES hsa-miR-216b-5p YES NO YES hsa-miR-217 YES YES NO hsa-miR-25-3p YES YES YES hsa-miR-296-3p YES YES NO hsa-miR-300 YES NO YES hsa-miR-301a-3p YES YES YES hsa-miR-301b-3p YES YES YES hsa-miR-30e-5p YES YES NO hsa-miR-320a YES YES NO hsa-miR-320b YES YES NO hsa-miR-320c YES YES NO hsa-miR-320d YES YES NO hsa-miR-323a-3p YES NO YES hsa-miR-32-5p YES YES YES hsa-miR-326 YES YES NO hsa-miR-330-3p YES NO YES hsa-miR-330-5p YES YES NO hsa-miR-340-5p YES YES YES hsa-miR-363-3p YES YES YES hsa-miR-367-3p YES YES YES hsa-miR-374a-5p YES YES NO hsa-miR-374b-5p YES YES NO hsa-miR-377-3p YES YES NO hsa-miR-381-3p YES NO YES hsa-miR-384 YES YES NO hsa-miR-411-5p YES YES NO hsa-miR-421 YES YES NO hsa-miR-429 YES YES NO hsa-miR-433-3p YES YES NO hsa-miR-454-3p YES YES YES hsa-miR-494-3p YES YES NO hsa-miR-495-3p YES NO NO hsa-miR-519d-3p YES NO YES hsa-miR-625-5p YES NO NO hsa-miR-758-3p YES YES NO hsa-miR-92a-3p YES YES YES hsa-miR-92b-3p YES YES YES hsa-miR-93-5p YES NO YES hsa-miR-96-5p YES YES YES Display: