ctcRbase

Entry Detail

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General Information

Database ID: PRAD09263 Cancer Type: prostate cancer Dataset: GSE104209 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: BCL2L2 Full Name: BCL2 like 2 Category: mRNA Synonyms: BCL-W|BCL2-L-2|BCLW|PPP1R51 Chromosome: chr14 Strand: + Coordinate: Start Site(bp): 23298790 End Site(bp): 23311759 Gene Summary: This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators. Expression of this gene in cells has been shown to contribute to reduced cell apoptosis under cytotoxic conditions. Studies of the related gene in mice indicated a role in the survival of NGF- and BDNF-dependent neurons. Mutation and knockout studies of the mouse gene demonstrated an essential role in adult spermatogenesis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream PABPN1 (poly(A) binding protein, nuclear 1) gene. [provided by RefSeq, Dec 2010] External Links: Ensembl ID: ENSG00000129473 HGNC ID: HGNC:995 Entrez Gene: 599

Expression Profile of BCL2L2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-103a-3p YES NO YES hsa-miR-106a-5p YES YES YES hsa-miR-106b-5p YES YES YES hsa-miR-107 YES NO YES hsa-miR-10a-5p YES NO YES hsa-miR-10b-5p YES NO YES hsa-miR-125a-5p YES NO YES hsa-miR-125b-5p YES NO YES hsa-miR-129-2-3p YES NO YES hsa-miR-133a-3p YES YES YES hsa-miR-133b YES YES YES hsa-miR-1-3p YES YES YES hsa-miR-140-5p YES YES YES hsa-miR-148a-3p YES NO YES hsa-miR-148b-3p YES NO YES hsa-miR-149-5p YES YES NO hsa-miR-152-3p YES NO YES hsa-miR-15a-5p YES YES YES hsa-miR-15b-5p YES YES YES hsa-miR-16-5p YES YES YES hsa-miR-17-5p YES YES YES hsa-miR-185-5p YES NO YES hsa-miR-193a-3p YES YES YES hsa-miR-193b-3p YES YES YES hsa-miR-195-5p YES YES YES hsa-miR-204-5p YES NO YES hsa-miR-206 YES YES YES hsa-miR-20a-5p YES YES YES hsa-miR-20b-5p YES YES YES hsa-miR-211-5p YES NO YES hsa-miR-224-5p YES YES NO hsa-miR-24-3p YES YES YES hsa-miR-29a-3p YES NO YES hsa-miR-29b-3p YES NO YES hsa-miR-29c-3p YES NO YES hsa-miR-326 YES YES YES hsa-miR-330-5p YES YES YES hsa-miR-338-3p YES NO YES hsa-miR-340-5p YES YES YES hsa-miR-342-3p YES YES NO hsa-miR-378a-3p YES YES YES hsa-miR-422a YES YES YES hsa-miR-424-5p YES YES YES hsa-miR-455-5p YES YES NO hsa-miR-490-3p YES YES NO hsa-miR-491-5p YES YES YES hsa-miR-497-5p YES YES YES hsa-miR-519d-3p YES YES YES hsa-miR-613 YES YES YES hsa-miR-655-3p YES NO YES hsa-miR-760 YES NO YES hsa-miR-873-5p YES YES NO hsa-miR-93-5p YES YES YES Display: