ctcRbase

Entry Detail

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General Information

Database ID: PRAD09286 Cancer Type: prostate cancer Dataset: GSE104209 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: NCOR2 Full Name: nuclear receptor corepressor 2 Category: mRNA Synonyms: CTG26|N-CoR2|SMAP270|SMRT|SMRTE|SMRTE-tau|TNRC14|TRAC|TRAC-1|TRAC1 Chromosome: chr12 Strand: - Coordinate: Start Site(bp): 124324415 End Site(bp): 124567589 Gene Summary: This gene encodes a nuclear receptor co-repressor that mediates transcriptional silencing of certain target genes. The encoded protein is a member of a family of thyroid hormone- and retinoic acid receptor-associated co-repressors. This protein acts as part of a multisubunit complex which includes histone deacetylases to modify chromatin structure that prevents basal transcriptional activity of target genes. Aberrant expression of this gene is associated with certain cancers. Alternate splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Apr 2011] External Links: Ensembl ID: ENSG00000196498 HGNC ID: HGNC:7673 Entrez Gene: 9612

Expression Profile of NCOR2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-10a-5p YES YES YES hsa-miR-10b-5p YES YES YES hsa-miR-125a-5p YES YES YES hsa-miR-125b-5p YES YES YES hsa-miR-1321 YES NO NO hsa-miR-132-3p YES YES NO hsa-miR-15a-5p YES YES YES hsa-miR-15b-5p YES YES YES hsa-miR-16-5p YES YES YES hsa-miR-184 YES YES YES hsa-miR-195-5p YES YES YES hsa-miR-200b-3p YES YES YES hsa-miR-200c-3p YES YES YES hsa-miR-29a-3p YES YES YES hsa-miR-29b-3p YES YES YES hsa-miR-29c-3p YES YES YES hsa-miR-30a-5p YES YES NO hsa-miR-30b-5p YES YES NO hsa-miR-30c-5p YES YES NO hsa-miR-30d-5p YES YES NO hsa-miR-30e-5p YES YES NO hsa-miR-31-5p YES YES NO hsa-miR-339-5p YES YES NO hsa-miR-424-5p YES YES YES hsa-miR-429 YES YES YES hsa-miR-455-3p YES NO NO hsa-miR-486-5p YES YES NO hsa-miR-491-5p YES YES NO hsa-miR-496 YES YES NO hsa-miR-497-5p YES YES YES hsa-miR-615-3p YES YES NO hsa-miR-9-5p YES YES YES Display: