ctcRbase

Entry Detail

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General Information

Database ID: PRAD09430 Cancer Type: prostate cancer Dataset: GSE104209 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: EYA4 Full Name: EYA transcriptional coactivator and phosphatase 4 Category: mRNA Synonyms: CMD1J|DFNA10 Chromosome: chr6 Strand: + Coordinate: Start Site(bp): 133240598 End Site(bp): 133532120 Gene Summary: This gene encodes a member of the eyes absent (EYA) family of proteins. The encoded protein may act as a transcriptional activator through its protein phosphatase activity, and it may be important for eye development, and for continued function of the mature organ of Corti. Mutations in this gene are associated with postlingual, progressive, autosomal dominant hearing loss at the deafness, autosomal dominant non-syndromic sensorineural 10 locus. The encoded protein is also a putative oncogene that mediates DNA repair, apoptosis, and innate immunity following DNA damage, cellular damage, and viral attack. Defects in this gene are also associated with dilated cardiomyopathy 1J. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2014] External Links: Ensembl ID: ENSG00000112319 HGNC ID: HGNC:3522 Entrez Gene: 2070

Expression Profile of EYA4 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-103a-3p YES YES NO hsa-miR-106a-5p YES YES NO hsa-miR-106b-5p YES YES NO hsa-miR-107 YES YES NO hsa-miR-124-3p YES YES YES hsa-miR-128-3p YES YES NO hsa-miR-129-5p YES YES NO hsa-miR-133a-3p YES YES YES hsa-miR-133b YES YES YES hsa-miR-135a-5p YES NO YES hsa-miR-135b-5p YES NO YES hsa-miR-139-5p YES YES YES hsa-miR-1-3p YES YES YES hsa-miR-142-5p YES NO YES hsa-miR-144-3p YES YES NO hsa-miR-145-5p YES YES YES hsa-miR-149-5p YES YES NO hsa-miR-15a-5p YES YES YES hsa-miR-15b-5p YES YES YES hsa-miR-16-5p YES YES YES hsa-miR-17-5p YES YES NO hsa-miR-194-5p YES NO YES hsa-miR-195-5p YES YES YES hsa-miR-196a-5p YES NO YES hsa-miR-196b-5p YES NO YES hsa-miR-206 YES YES YES hsa-miR-208a-3p YES YES NO hsa-miR-208b-3p YES YES NO hsa-miR-20a-5p YES YES NO hsa-miR-20b-5p YES YES NO hsa-miR-224-5p YES YES YES hsa-miR-27a-3p YES YES YES hsa-miR-27b-3p YES YES YES hsa-miR-320a YES YES YES hsa-miR-320b YES YES YES hsa-miR-320c YES YES YES hsa-miR-320d YES YES YES hsa-miR-324-5p YES YES YES hsa-miR-371a-5p YES YES NO hsa-miR-377-3p YES YES YES hsa-miR-382-5p YES YES NO hsa-miR-409-3p YES NO YES hsa-miR-424-5p YES YES YES hsa-miR-431-5p YES NO YES hsa-miR-433-3p NO YES YES hsa-miR-497-5p YES YES YES hsa-miR-499a-5p YES YES NO hsa-miR-506-3p YES YES NO hsa-miR-519d-3p YES YES NO hsa-miR-543 YES YES YES hsa-miR-613 YES YES YES hsa-miR-93-5p YES YES NO Display: