Entry Detail



General Information

Database ID:PRAD09493
Cancer Type:prostate cancer
Dataset:GSE104209
CTCs/CTM Isolation Method:CTC-iChip



Gene Information

ncRNA Symbol:SLAMF6
Full Name:SLAM family member 6
Category:mRNA
Synonyms:CD352|KALI|KALIb|Ly108|NTB-A|NTBA|SF2000
Chromosome:chr1
Strand:-
Coordinate:
Start Site(bp):160485030End Site(bp):160523262
Gene Summary:The protein encoded by this gene is a type I transmembrane protein, belonging to the CD2 subfamily of the immunoglobulin superfamily. This encoded protein is expressed on Natural killer (NK), T, and B lymphocytes. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It functions as a coreceptor in the process of NK cell activation. It can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, May 2010]
External Links:
Ensembl ID:ENSG00000162739
HGNC ID:HGNC:21392
Entrez Gene:114836



Expression Profile of SLAMF6 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-let-7a-5p
YES
YES
NO
hsa-let-7b-5p
YES
YES
NO
hsa-let-7c-5p
YES
YES
NO
hsa-let-7d-5p
YES
YES
NO
hsa-let-7e-5p
YES
YES
NO
hsa-let-7f-5p
YES
YES
NO
hsa-let-7g-5p
YES
YES
NO
hsa-let-7i-5p
YES
YES
NO
hsa-miR-155-5p
YES
YES
NO
hsa-miR-221-3p
YES
YES
NO
hsa-miR-222-3p
YES
YES
NO
hsa-miR-376c-3p
YES
YES
NO
hsa-miR-485-5p
YES
YES
NO
hsa-miR-665
YES
NO
YES
hsa-miR-98-5p
YES
YES
NO
Display: