| ncRNA Symbol: | AFDN | | Full Name: | afadin, adherens junction formation factor | | Category: | mRNA | | Synonyms: | AF6|MLL-AF6|MLLT4|l-afadin | | Chromosome: | chr6 | | Strand: | + | | Coordinate: | | Start Site(bp): | 167826922 | End Site(bp): | 167972023 | | | Gene Summary: | This gene encodes a multi-domain protein involved in signaling and organization of cell junctions during embryogenesis. It has also been identified as the fusion partner of acute lymphoblastic leukemia (ALL-1) gene, involved in acute myeloid leukemias with t(6;11)(q27;q23) translocation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, however, not all have been fully characterized.[provided by RefSeq, May 2011] | | External Links: | |
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