ctcRbase

Entry Detail

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General Information

Database ID: SKCM00980 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: KYNU Full Name: kynureninase Category: mRNA Synonyms: KYNUU|VCRL2 Chromosome: chr2 Strand: + Coordinate: Start Site(bp): 142877498 End Site(bp): 143055832 Gene Summary: Kynureninase is a pyridoxal-5'-phosphate (pyridoxal-P) dependent enzyme that catalyzes the cleavage of L-kynurenine and L-3-hydroxykynurenine into anthranilic and 3-hydroxyanthranilic acids, respectively. Kynureninase is involved in the biosynthesis of NAD cofactors from tryptophan through the kynurenine pathway. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2010] External Links: Ensembl ID: ENSG00000115919 HGNC ID: HGNC:6469 Entrez Gene: 8942

Expression Profile of KYNU Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-132-3p YES YES NO hsa-miR-200b-3p YES YES NO hsa-miR-200c-3p YES YES NO hsa-miR-212-3p YES YES NO hsa-miR-221-3p YES YES NO hsa-miR-222-3p YES YES NO hsa-miR-28-3p YES NO YES hsa-miR-429 YES YES NO hsa-miR-542-3p YES YES NO Display: