ctcRbase

Entry Detail

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General Information

Database ID: SKCM01172 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: MRPS10 Full Name: mitochondrial ribosomal protein S10 Category: mRNA Synonyms: MRP-S10|PNAS-122 Chromosome: chr6 Strand: - Coordinate: Start Site(bp): 42206801 End Site(bp): 42217865 Gene Summary: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S10P family. Pseudogenes corresponding to this gene are found on chromosomes 1q, 3p, and 9p. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000048544 HGNC ID: HGNC:14502 Entrez Gene: 55173

Expression Profile of MRPS10 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-139-5p YES YES NO hsa-miR-140-5p YES YES NO hsa-miR-155-5p YES YES NO hsa-miR-186-5p YES YES NO hsa-miR-21-5p YES YES NO hsa-miR-300 YES YES NO hsa-miR-381-3p YES YES NO hsa-miR-590-5p YES YES NO hsa-miR-625-5p YES NO NO Display: