ctcRbase

Entry Detail

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General Information

Database ID: SKCM01194 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: CDK1 Full Name: cyclin dependent kinase 1 Category: mRNA Synonyms: CDC2|CDC28A|P34CDC2 Chromosome: chr10 Strand: + Coordinate: Start Site(bp): 60778331 End Site(bp): 60794852 Gene Summary: The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009] External Links: Ensembl ID: ENSG00000170312 HGNC ID: HGNC:1722 Entrez Gene: 983

Expression Profile of CDK1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-129-5p YES YES NO hsa-miR-143-3p NO YES YES hsa-miR-186-5p YES YES NO hsa-miR-208a-3p YES YES NO hsa-miR-208b-3p YES YES NO hsa-miR-31-5p NO YES YES hsa-miR-335-5p YES YES NO hsa-miR-410-3p YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-499a-5p YES YES NO Display: