ctcRbase

Entry Detail

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General Information

Database ID: SKCM01247 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: SF3A3 Full Name: splicing factor 3a subunit 3 Category: mRNA Synonyms: PRP9|PRPF9|SAP61|SF3a60 Chromosome: chr1 Strand: - Coordinate: Start Site(bp): 37956975 End Site(bp): 37990921 Gene Summary: This gene encodes subunit 3 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 3 interacts with subunit 1 through its amino-terminus while the zinc finger domain of subunit 3 plays a role in its binding to the 15S U2 snRNP. This gene has a pseudogene on chromosome 20. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016] External Links: Ensembl ID: ENSG00000183431 HGNC ID: HGNC:10767 Entrez Gene: 10946

Expression Profile of SF3A3 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-let-7a-5p YES YES NO hsa-let-7c-5p YES YES NO hsa-let-7e-5p YES YES NO hsa-miR-133a-3p YES YES NO hsa-miR-133b YES YES NO hsa-miR-149-5p YES YES NO hsa-miR-15a-5p YES YES NO hsa-miR-15b-5p YES YES NO hsa-miR-16-5p YES YES NO hsa-miR-190a-5p YES YES NO hsa-miR-190b YES YES NO hsa-miR-195-5p YES YES NO hsa-miR-216a-5p YES YES NO hsa-miR-218-5p YES YES NO hsa-miR-320a YES YES NO hsa-miR-320b YES YES NO hsa-miR-320c YES YES NO hsa-miR-320d YES YES NO hsa-miR-326 YES YES NO hsa-miR-330-5p YES YES NO hsa-miR-338-3p YES YES YES hsa-miR-340-5p YES YES NO hsa-miR-371a-5p YES YES NO hsa-miR-379-5p YES YES NO hsa-miR-410-3p YES YES NO hsa-miR-424-5p YES YES NO hsa-miR-491-5p YES YES NO hsa-miR-496 YES YES NO hsa-miR-497-5p YES YES NO hsa-miR-532-5p YES NO YES Display: