ctcRbase

Entry Detail

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General Information

Database ID: SKCM01270 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: SPP1 Full Name: secreted phosphoprotein 1 Category: mRNA Synonyms: BNSP|BSPI|ETA-1|OPN Chromosome: chr4 Strand: + Coordinate: Start Site(bp): 87975650 End Site(bp): 87983426 Gene Summary: The protein encoded by this gene is involved in the attachment of osteoclasts to the mineralized bone matrix. The encoded protein is secreted and binds hydroxyapatite with high affinity. The osteoclast vitronectin receptor is found in the cell membrane and may be involved in the binding to this protein. This protein is also a cytokine that upregulates expression of interferon-gamma and interleukin-12. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011] External Links: Ensembl ID: ENSG00000118785 HGNC ID: HGNC:11255 Entrez Gene: 6696

Expression Profile of SPP1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-181a-5p YES YES NO hsa-miR-181b-5p YES YES NO hsa-miR-181c-5p YES YES NO hsa-miR-181d-5p YES YES NO hsa-miR-33b-5p YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-376c-3p YES YES NO hsa-miR-377-3p YES YES NO hsa-miR-433-3p YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-542-3p YES YES NO Display: