ctcRbase

Entry Detail

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General Information

Database ID: SKCM01284 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: XRCC4 Full Name: X-ray repair cross complementing 4 Category: mRNA Synonyms: SSMED Chromosome: chr5 Strand: + Coordinate: Start Site(bp): 83077498 End Site(bp): 83353787 Gene Summary: The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand breaks. This protein plays a role in both non-homologous end joining and the completion of V(D)J recombination. Mutations in this gene can cause short stature, microcephaly, and endocrine dysfunction (SSMED). Alternative splicing generates several transcript variants. [provided by RefSeq, Dec 2015] External Links: Ensembl ID: ENSG00000152422 HGNC ID: HGNC:12831 Entrez Gene: 7518

Expression Profile of XRCC4 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-199a-5p YES YES NO hsa-miR-361-5p YES YES NO hsa-miR-374a-5p YES YES NO hsa-miR-374b-5p YES YES NO hsa-miR-376c-3p YES YES NO hsa-miR-455-5p YES YES NO Display: