Entry Detail



General Information

Database ID:SKCM01494
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:MLX
Full Name:MLX, MAX dimerization protein
Category:mRNA
Synonyms:MAD7|MXD7|TCFL4|TF4|bHLHd13
Chromosome:chr17
Strand:+
Coordinate:
Start Site(bp):42567068End Site(bp):42573239
Gene Summary:The product of this gene belongs to the family of basic helix-loop-helix leucine zipper (bHLH-Zip) transcription factors. These factors form heterodimers with Mad proteins and play a role in proliferation, determination and differentiation. This gene product may act to diversify Mad family function by its restricted association with a subset of the Mad family of transcriptional repressors, namely, Mad1 and Mad4. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
External Links:
Ensembl ID:ENSG00000108788
HGNC ID:HGNC:11645
Entrez Gene:6945



Expression Profile of MLX Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-103a-3p
YES
YES
NO
hsa-miR-107
YES
YES
NO
hsa-miR-1271-5p
YES
YES
NO
hsa-miR-141-3p
YES
YES
NO
hsa-miR-142-3p
YES
YES
NO
hsa-miR-146a-5p
YES
YES
NO
hsa-miR-146b-5p
YES
YES
NO
hsa-miR-182-5p
YES
YES
YES
hsa-miR-199a-5p
YES
YES
NO
hsa-miR-199b-5p
YES
YES
NO
hsa-miR-200a-3p
YES
YES
NO
hsa-miR-217
YES
YES
NO
hsa-miR-24-3p
YES
YES
NO
hsa-miR-326
YES
YES
NO
hsa-miR-330-5p
YES
YES
NO
hsa-miR-335-5p
YES
YES
NO
hsa-miR-33a-5p
YES
YES
NO
hsa-miR-33b-5p
YES
YES
NO
hsa-miR-340-5p
YES
YES
NO
hsa-miR-365a-3p
YES
YES
NO
hsa-miR-374a-5p
YES
YES
NO
hsa-miR-374b-5p
YES
YES
NO
hsa-miR-410-3p
YES
YES
NO
hsa-miR-485-5p
YES
YES
NO
hsa-miR-495-3p
YES
YES
NO
hsa-miR-96-5p
YES
YES
NO
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