ctcRbase

Entry Detail

---



General Information

Database ID: SKCM01503 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: AIMP1 Full Name: aminoacyl tRNA synthetase complex interacting multifunctional protein 1 Category: mRNA Synonyms: EMAP2|EMAPII|HLD3|SCYE1|p43 Chromosome: chr4 Strand: + Coordinate: Start Site(bp): 106315544 End Site(bp): 106349226 Gene Summary: The protein encoded by this gene is a cytokine that is specifically induced by apoptosis, and it is involved in the control of angiogenesis, inflammation, and wound healing. The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor. The precursor protein is identical to the p43 subunit, which is associated with the multi-tRNA synthetase complex, and it modulates aminoacylation activity of tRNA synthetase in normal cells. This protein is also involved in the stimulation of inflammatory responses after proteolytic cleavage in tumor cells. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene has been identified on chromosome 20. [provided by RefSeq, Dec 2008] External Links: Ensembl ID: ENSG00000164022 HGNC ID: HGNC:10648 Entrez Gene: 9255

Expression Profile of AIMP1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-185-5p YES YES NO hsa-miR-186-5p YES YES NO hsa-miR-216a-5p YES YES NO hsa-miR-22-3p YES YES NO hsa-miR-320a YES YES NO hsa-miR-320b YES YES NO hsa-miR-320c YES YES NO hsa-miR-320d YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-370-3p YES YES NO Display: