ctcRbase

Entry Detail

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General Information

Database ID: SKCM01512 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: DDX46 Full Name: DEAD-box helicase 46 Category: mRNA Synonyms: PRPF5|Prp5 Chromosome: chr5 Strand: + Coordinate: Start Site(bp): 134758771 End Site(bp): 134855133 Gene Summary: This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a component of the 17S U2 snRNP complex; it plays an important role in pre-mRNA splicing. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2014] External Links: Ensembl ID: ENSG00000145833 HGNC ID: HGNC:18681 Entrez Gene: 9879

Expression Profile of DDX46 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-129-5p YES YES NO hsa-miR-135a-5p YES YES NO hsa-miR-135b-5p YES YES NO hsa-miR-140-5p YES YES NO hsa-miR-145-5p YES YES NO hsa-miR-186-5p YES YES NO hsa-miR-224-5p YES YES NO hsa-miR-24-3p YES YES NO hsa-miR-299-3p YES YES NO hsa-miR-29a-3p YES YES YES hsa-miR-29b-3p YES YES YES hsa-miR-29c-3p YES YES YES hsa-miR-30a-5p YES NO YES hsa-miR-30b-5p YES NO YES hsa-miR-30c-5p YES NO YES hsa-miR-30d-5p YES NO YES hsa-miR-30e-5p YES NO YES hsa-miR-376a-3p YES YES NO hsa-miR-376b-3p YES YES NO hsa-miR-382-5p YES YES NO hsa-miR-448 YES YES NO hsa-miR-491-5p YES YES NO hsa-miR-494-3p YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-499a-5p YES YES NO hsa-miR-543 YES YES YES hsa-miR-873-5p YES YES NO hsa-miR-9-5p YES YES NO Display: