ctcRbase

Entry Detail

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General Information

Database ID: SKCM01554 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: CBX1 Full Name: chromobox 1 Category: mRNA Synonyms: CBX|HP1-BETA|HP1Hs-beta|HP1Hsbeta|M31|MOD1|p25beta Chromosome: chr17 Strand: - Coordinate: Start Site(bp): 48070052 End Site(bp): 48101521 Gene Summary: This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family . The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The protein may play an important role in the epigenetic control of chromatin structure and gene expression. Several related pseudogenes are located on chromosomes 1, 3, and X. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000108468 HGNC ID: HGNC:1551 Entrez Gene: 10951

Expression Profile of CBX1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-129-5p YES YES NO hsa-miR-132-3p YES YES NO hsa-miR-134-5p YES YES NO hsa-miR-139-5p YES YES NO hsa-miR-141-3p YES NO YES hsa-miR-144-3p YES YES NO hsa-miR-147a YES NO NO hsa-miR-149-5p YES YES NO hsa-miR-186-5p YES YES NO hsa-miR-193a-3p YES YES NO hsa-miR-19a-3p YES YES NO hsa-miR-19b-3p YES YES NO hsa-miR-200a-3p YES NO YES hsa-miR-204-5p YES YES NO hsa-miR-205-5p YES YES YES hsa-miR-208a-3p YES YES NO hsa-miR-208b-3p YES YES NO hsa-miR-211-5p YES YES NO hsa-miR-212-3p YES YES NO hsa-miR-27a-3p YES YES NO hsa-miR-27b-3p YES YES NO hsa-miR-329-3p YES YES NO hsa-miR-362-3p YES YES NO hsa-miR-376a-3p YES YES NO hsa-miR-376b-3p YES YES NO hsa-miR-376c-3p YES YES NO hsa-miR-378a-3p YES YES NO hsa-miR-422a YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-532-3p YES NO YES hsa-miR-542-3p YES YES NO hsa-miR-599 YES YES NO hsa-miR-876-5p YES YES NO hsa-miR-9-5p YES YES NO Display: