ctcRbase

Entry Detail

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General Information

Database ID: SKCM01555 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: CDK2 Full Name: cyclin dependent kinase 2 Category: mRNA Synonyms: CDKN2|p33(CDK2) Chromosome: chr12 Strand: + Coordinate: Start Site(bp): 55966769 End Site(bp): 55972784 Gene Summary: This gene encodes a member of a family of serine/threonine protein kinases that participate in cell cycle regulation. The encoded protein is the catalytic subunit of the cyclin-dependent protein kinase complex, which regulates progression through the cell cycle. Activity of this protein is especially critical during the G1 to S phase transition. This protein associates with and regulated by other subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A), and p27Kip1 (CDKN1B). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014] External Links: Ensembl ID: ENSG00000123374 HGNC ID: HGNC:1771 Entrez Gene: 1017

Expression Profile of CDK2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-140-5p YES YES NO hsa-miR-141-3p YES YES NO hsa-miR-182-5p YES YES NO hsa-miR-186-5p YES YES NO hsa-miR-18a-5p YES YES YES hsa-miR-18b-5p YES YES YES hsa-miR-200a-3p YES YES NO hsa-miR-200b-3p YES YES YES hsa-miR-200c-3p YES YES YES hsa-miR-214-3p YES YES NO hsa-miR-29a-3p YES YES NO hsa-miR-29b-3p YES YES NO hsa-miR-29c-3p YES YES NO hsa-miR-302a-3p YES NO YES hsa-miR-302b-3p YES NO YES hsa-miR-302c-3p YES NO YES hsa-miR-302d-3p YES NO YES hsa-miR-302e YES NO YES hsa-miR-335-5p YES YES NO hsa-miR-339-5p YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-372-3p YES NO YES hsa-miR-373-3p YES NO YES hsa-miR-375 YES YES NO hsa-miR-410-3p YES YES NO hsa-miR-429 YES YES YES hsa-miR-490-3p YES YES NO hsa-miR-520a-3p YES NO YES hsa-miR-520b YES NO YES hsa-miR-520c-3p YES NO YES hsa-miR-520d-3p YES NO YES hsa-miR-520e YES NO YES hsa-miR-542-3p YES YES NO hsa-miR-625-5p YES NO NO Display: