ctcRbase

Entry Detail

---



General Information

Database ID: SKCM01673 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: WRB Full Name: tryptophan rich basic protein Category: mRNA Synonyms: CHD5|GET1 Chromosome: chr21 Strand: + Coordinate: Start Site(bp): 39380244 End Site(bp): 39428528 Gene Summary: This gene is located in the candidate region for congenital heart disease (CHD) in Down syndrome (DS). It encodes a basic protein that functions as a receptor that promotes insertion of tail-anchored proteins in the endoplasmic reticulum membrane. This gene is located at a maternally-methylated differentially methylated region (DMR); however, its transcription may be biallelic, not imprinted. Alternative splicing results in different transcript variants. A pseudogene has been defined on chromosome 4. [provided by RefSeq, Apr 2017] External Links: Ensembl ID: ENSG00000182093 HGNC ID: HGNC:12790 Entrez Gene: 7485

Expression Profile of WRB Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-1297 YES YES NO hsa-miR-140-5p YES YES NO hsa-miR-141-3p YES YES NO hsa-miR-142-3p YES YES NO hsa-miR-145-5p YES YES NO hsa-miR-182-5p YES YES NO hsa-miR-186-5p YES YES NO hsa-miR-200a-3p YES YES NO hsa-miR-23a-3p YES YES NO hsa-miR-23b-3p YES YES NO hsa-miR-26a-5p YES YES NO hsa-miR-26b-5p YES YES NO hsa-miR-378a-3p YES YES NO hsa-miR-382-5p YES YES NO hsa-miR-421 YES YES NO hsa-miR-422a YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-499a-5p YES YES NO hsa-miR-542-3p YES YES NO Display: