ctcRbase

Entry Detail

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General Information

Database ID: SKCM01675 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: DENR Full Name: density regulated re-initiation and release factor Category: mRNA Synonyms: DRP|DRP1|SMAP-3 Chromosome: chr12 Strand: + Coordinate: Start Site(bp): 122752774 End Site(bp): 122771064 Gene Summary: This gene encodes a protein whose expression was found to increase in cultured cells at high density but not during growth arrest. This gene was also shown to have increased expression in cells overexpressing HER-2/neu proto-oncogene. The protein contains an SUI1 domain. In budding yeast, SUI1 is a translation initiation factor that along with eIF-2 and the initiator tRNA-Met, directs the ribosome to the proper translation start site. Proteins similar to SUI have been found in mammals, insects, and plants. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000139726 HGNC ID: HGNC:2769 Entrez Gene: 8562

Expression Profile of DENR Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES YES NO hsa-miR-1271-5p YES NO YES hsa-miR-139-5p YES YES YES hsa-miR-15a-5p YES YES NO hsa-miR-15b-5p YES YES NO hsa-miR-16-5p YES YES NO hsa-miR-182-5p YES YES YES hsa-miR-195-5p YES YES NO hsa-miR-200b-3p YES YES NO hsa-miR-200c-3p YES YES NO hsa-miR-204-5p YES YES YES hsa-miR-211-5p YES YES YES hsa-miR-217 YES YES YES hsa-miR-224-5p YES YES YES hsa-miR-340-5p YES YES NO hsa-miR-342-3p YES YES NO hsa-miR-371a-5p YES YES NO hsa-miR-383-5p YES YES NO hsa-miR-421 YES YES NO hsa-miR-424-5p YES YES NO hsa-miR-429 YES YES NO hsa-miR-485-5p YES YES NO hsa-miR-497-5p YES YES NO hsa-miR-582-5p YES NO YES hsa-miR-96-5p YES NO YES Display: