ctcRbase

Entry Detail

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General Information

Database ID: SKCM01684 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: CENPF Full Name: centromere protein F Category: mRNA Synonyms: CENF|CILD31|PRO1779|STROMS|hcp-1 Chromosome: chr1 Strand: + Coordinate: Start Site(bp): 214603195 End Site(bp): 214664588 Gene Summary: This gene encodes a protein that associates with the centromere-kinetochore complex. The protein is a component of the nuclear matrix during the G2 phase of interphase. In late G2 the protein associates with the kinetochore and maintains this association through early anaphase. It localizes to the spindle midzone and the intracellular bridge in late anaphase and telophase, respectively, and is thought to be subsequently degraded. The localization of this protein suggests that it may play a role in chromosome segregation during mitotis. It is thought to form either a homodimer or heterodimer. Autoantibodies against this protein have been found in patients with cancer or graft versus host disease. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000117724 HGNC ID: HGNC:1857 Entrez Gene: 1063

Expression Profile of CENPF Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-133a-3p YES YES NO hsa-miR-133b YES YES NO hsa-miR-193b-3p YES YES NO hsa-miR-194-5p YES YES NO hsa-miR-205-5p YES YES YES hsa-miR-208a-3p YES YES NO hsa-miR-208b-3p YES YES NO hsa-miR-28-5p YES YES NO hsa-miR-33a-5p YES YES NO hsa-miR-33b-5p YES YES NO hsa-miR-376c-3p YES YES NO hsa-miR-384 YES YES NO hsa-miR-499a-5p YES YES NO hsa-miR-520f-3p YES NO YES hsa-miR-708-5p YES YES NO hsa-miR-874-3p YES YES NO Display: