ctcRbase

Entry Detail

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General Information

Database ID: SKCM01718 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: RHOQ Full Name: ras homolog family member Q Category: mRNA Synonyms: ARHQ|HEL-S-42|RASL7A|TC10|TC10A Chromosome: chr2 Strand: + Coordinate: Start Site(bp): 46541806 End Site(bp): 46583121 Gene Summary: This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The encoded protein is an important signalling protein for sarcomere assembly and has been shown to play a significant role in the exocytosis of the solute carrier family 2, facilitated glucose transporter member 4 and other proteins, possibly acting as the signal that turns on the membrane fusion machinery. Three related pseudogene have been identified on chromosomes 2 and 14. [provided by RefSeq, Aug 2011] External Links: Ensembl ID: ENSG00000119729 HGNC ID: HGNC:17736 Entrez Gene: 23433

Expression Profile of RHOQ Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES YES YES hsa-miR-1224-5p YES NO YES hsa-miR-125a-5p YES YES YES hsa-miR-125b-5p YES YES YES hsa-miR-1271-5p YES NO YES hsa-miR-1297 YES YES YES hsa-miR-134-5p YES YES YES hsa-miR-142-5p YES NO YES hsa-miR-155-5p YES NO YES hsa-miR-182-5p YES NO YES hsa-miR-197-3p YES YES NO hsa-miR-216a-5p YES NO YES hsa-miR-216b-5p YES YES YES hsa-miR-218-5p YES NO YES hsa-miR-219a-5p YES NO YES hsa-miR-26a-5p YES YES YES hsa-miR-26b-5p YES YES YES hsa-miR-300 YES YES YES hsa-miR-328-3p YES YES NO hsa-miR-374a-5p YES YES YES hsa-miR-374b-5p YES YES YES hsa-miR-381-3p YES YES YES hsa-miR-382-5p YES YES NO hsa-miR-411-5p YES YES NO hsa-miR-433-3p YES YES YES hsa-miR-486-5p YES NO YES hsa-miR-543 YES YES YES hsa-miR-582-5p YES NO YES hsa-miR-758-3p YES YES YES hsa-miR-96-5p YES NO YES Display: