ctcRbase

Entry Detail

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General Information

Database ID: SKCM01736 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: BMI1 Full Name: BMI1 proto-oncogene, polycomb ring finger Category: mRNA Synonyms: FLVI2/BMI1|PCGF4|RNF51|flvi-2/bmi-1 Chromosome: chr10 Strand: + Coordinate: Start Site(bp): 22321211 End Site(bp): 22331484 Gene Summary: This gene encodes a ring finger protein that is major component of the polycomb group complex 1 (PRC1). This complex functions through chromatin remodeling as an essential epigenetic repressor of multiple regulatory genes involved in embryonic development and self-renewal in somatic stem cells. This protein also plays a central role in DNA damage repair. This gene is an oncogene and aberrant expression is associated with numerous cancers and is associated with resistance to certain chemotherapies. A pseudogene of this gene is found on chromosome X. Read-through transcription also exists between this gene and the upstream COMM domain containing 3 (COMMD3) gene. [provided by RefSeq, Sep 2015] External Links: Ensembl ID: ENSG00000168283 HGNC ID: HGNC:1066 Entrez Gene: 648

Expression Profile of BMI1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-128-3p YES YES YES hsa-miR-134-5p YES YES NO hsa-miR-135a-5p YES YES NO hsa-miR-135b-5p YES YES NO hsa-miR-139-5p YES YES NO hsa-miR-141-3p YES YES NO hsa-miR-154-5p YES YES NO hsa-miR-183-5p YES NO YES hsa-miR-194-5p YES YES NO hsa-miR-200a-3p YES YES NO hsa-miR-200b-3p YES YES YES hsa-miR-200c-3p YES YES YES hsa-miR-208a-3p YES YES NO hsa-miR-208b-3p YES YES NO hsa-miR-219a-2-3p YES NO YES hsa-miR-221-3p YES YES NO hsa-miR-222-3p YES YES NO hsa-miR-224-5p YES YES NO hsa-miR-27a-3p YES YES YES hsa-miR-27b-3p YES YES YES hsa-miR-300 YES YES NO hsa-miR-30a-5p YES YES NO hsa-miR-30b-5p YES YES NO hsa-miR-30c-5p YES YES NO hsa-miR-30d-5p YES YES NO hsa-miR-30e-5p YES YES NO hsa-miR-320a YES YES YES hsa-miR-320b YES YES YES hsa-miR-320c YES YES YES hsa-miR-320d YES YES YES hsa-miR-329-3p YES YES NO hsa-miR-330-3p YES NO YES hsa-miR-340-5p YES YES NO hsa-miR-362-3p YES YES NO hsa-miR-365a-3p YES NO YES hsa-miR-374a-5p YES YES NO hsa-miR-374b-5p YES YES NO hsa-miR-376c-3p YES YES YES hsa-miR-381-3p YES YES NO hsa-miR-429 YES YES YES hsa-miR-431-5p YES YES NO hsa-miR-448 YES YES NO hsa-miR-452-5p YES NO YES hsa-miR-455-5p YES YES NO hsa-miR-487a-3p YES NO YES hsa-miR-491-5p YES YES NO hsa-miR-494-3p YES YES NO hsa-miR-495-3p YES YES YES hsa-miR-758-3p YES YES NO hsa-miR-873-5p YES YES NO Display: