Entry Detail



General Information

Database ID:SKCM01824
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:TXNDC12
Full Name:thioredoxin domain containing 12
Category:mRNA
Synonyms:AG1|AGR1|ERP16|ERP18|ERP19|PDIA16|TLP19|hAG-1|hTLP19
Chromosome:chr1
Strand:-
Coordinate:
Start Site(bp):52020131End Site(bp):52056171
Gene Summary:This gene encodes a member of the thioredoxin superfamily. Members of this family are characterized by a conserved active motif called the thioredoxin fold that catalyzes disulfide bond formation and isomerization. This protein localizes to the endoplasmic reticulum and has a single atypical active motif. The encoded protein is mainly involved in catalyzing native disulfide bond formation and displays activity similar to protein-disulfide isomerases. This protein may play a role in defense against endoplasmic reticulum stress. Alternate splicing results in both coding and non-coding variants. [provided by RefSeq, Mar 2012]
External Links:
Ensembl ID:ENSG00000117862
HGNC ID:HGNC:24626
Entrez Gene:51060



Expression Profile of TXNDC12 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-128-3p
YES
YES
NO
hsa-miR-129-5p
YES
YES
NO
hsa-miR-155-5p
YES
YES
NO
hsa-miR-181a-5p
YES
YES
YES
hsa-miR-181b-5p
YES
YES
YES
hsa-miR-181c-5p
YES
YES
YES
hsa-miR-181d-5p
YES
YES
YES
hsa-miR-197-3p
YES
YES
NO
hsa-miR-199a-5p
YES
YES
NO
hsa-miR-199b-5p
YES
YES
NO
hsa-miR-19a-3p
YES
YES
NO
hsa-miR-19b-3p
YES
YES
NO
hsa-miR-30a-5p
YES
YES
NO
hsa-miR-30b-5p
YES
YES
NO
hsa-miR-30c-5p
YES
YES
NO
hsa-miR-30d-5p
YES
YES
NO
hsa-miR-30e-5p
YES
YES
NO
hsa-miR-346
YES
YES
NO
hsa-miR-365a-3p
YES
YES
NO
hsa-miR-370-3p
YES
YES
NO
hsa-miR-485-5p
YES
YES
NO
hsa-miR-582-5p
YES
NO
YES
hsa-miR-599
YES
YES
NO
hsa-miR-876-5p
YES
YES
NO
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