ctcRbase

Entry Detail

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General Information

Database ID: SKCM01850 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: RRM2 Full Name: ribonucleotide reductase regulatory subunit M2 Category: mRNA Synonyms: R2|RR2|RR2M Chromosome: chr2 Strand: + Coordinate: Start Site(bp): 10120698 End Site(bp): 10131419 Gene Summary: This gene encodes one of two non-identical subunits for ribonucleotide reductase. This reductase catalyzes the formation of deoxyribonucleotides from ribonucleotides. Synthesis of the encoded protein (M2) is regulated in a cell-cycle dependent fashion. Transcription from this gene can initiate from alternative promoters, which results in two isoforms that differ in the lengths of their N-termini. Related pseudogenes have been identified on chromosomes 1 and X. [provided by RefSeq, Sep 2009] External Links: Ensembl ID: ENSG00000171848 HGNC ID: HGNC:10452 Entrez Gene: 6241

Expression Profile of RRM2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-let-7a-5p YES YES YES hsa-let-7b-5p YES YES YES hsa-let-7c-5p YES YES YES hsa-let-7d-5p YES YES YES hsa-let-7e-5p YES YES YES hsa-let-7f-5p YES YES YES hsa-let-7g-5p YES YES YES hsa-let-7i-5p YES YES YES hsa-miR-106a-5p YES YES YES hsa-miR-106b-5p YES YES YES hsa-miR-125a-5p YES YES NO hsa-miR-125b-5p YES YES NO hsa-miR-17-5p YES YES YES hsa-miR-197-3p YES YES NO hsa-miR-204-5p NO YES YES hsa-miR-20a-5p YES YES YES hsa-miR-20b-5p YES YES YES hsa-miR-211-5p NO YES YES hsa-miR-30a-5p YES YES NO hsa-miR-30b-5p YES YES NO hsa-miR-30c-5p YES YES NO hsa-miR-30d-5p YES YES NO hsa-miR-30e-5p YES YES NO hsa-miR-31-5p YES YES NO hsa-miR-342-3p YES YES NO hsa-miR-376c-3p YES YES NO hsa-miR-377-3p YES YES NO hsa-miR-485-5p YES YES YES hsa-miR-495-3p YES YES NO hsa-miR-519d-3p YES YES YES hsa-miR-874-3p YES YES NO hsa-miR-93-5p YES YES YES hsa-miR-98-5p YES YES YES Display: