ctcRbase

Entry Detail

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General Information

Database ID: SKCM01851 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: TMX1 Full Name: thioredoxin related transmembrane protein 1 Category: mRNA Synonyms: PDIA11|TMX|TXNDC|TXNDC1 Chromosome: chr14 Strand: + Coordinate: Start Site(bp): 51240162 End Site(bp): 51257546 Gene Summary: This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, and one transmembrane domain. Unlike most members of this gene family, it lacks a C-terminal ER-retention sequence. The mature membrane-bound protein can both oxidize and reduce disulfide bonds and acts selectively on membrane-associated polypeptides. [provided by RefSeq, Jan 2017] External Links: Ensembl ID: ENSG00000139921 HGNC ID: HGNC:15487 Entrez Gene: 81542

Expression Profile of TMX1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-1271-5p YES YES YES hsa-miR-128-3p YES YES YES hsa-miR-1297 YES YES NO hsa-miR-137 YES YES YES hsa-miR-140-5p YES YES NO hsa-miR-146a-5p YES YES NO hsa-miR-146b-5p YES YES NO hsa-miR-151a-3p YES NO YES hsa-miR-153-3p YES NO YES hsa-miR-154-5p YES YES NO hsa-miR-196a-5p YES YES YES hsa-miR-196b-5p YES YES YES hsa-miR-200b-3p YES YES NO hsa-miR-200c-3p YES YES NO hsa-miR-218-5p YES YES YES hsa-miR-223-3p YES YES NO hsa-miR-224-5p YES YES YES hsa-miR-26a-5p YES YES NO hsa-miR-26b-5p YES YES NO hsa-miR-27a-3p YES YES YES hsa-miR-27b-3p YES YES YES hsa-miR-300 YES YES NO hsa-miR-323a-3p YES NO YES hsa-miR-377-3p YES YES YES hsa-miR-381-3p YES YES NO hsa-miR-429 YES YES NO hsa-miR-431-5p YES YES NO hsa-miR-448 YES NO YES hsa-miR-875-5p YES YES NO hsa-miR-96-5p YES YES YES Display: