ctcRbase

Entry Detail

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General Information

Database ID: SKCM01879 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: PIAS1 Full Name: protein inhibitor of activated STAT 1 Category: mRNA Synonyms: DDXBP1|GBP|GU/RH-II|ZMIZ3 Chromosome: chr15 Strand: + Coordinate: Start Site(bp): 68054179 End Site(bp): 68198603 Gene Summary: This gene encodes a member of the protein inhibitor of activated STAT (PIAS) family. PIAS proteins function as SUMO E3 ligases and play important roles in many cellular processes by mediating the sumoylation of target proteins. This protein plays a central role as a transcriptional coregulator of numerous cellular pathways includign the STAT1 and nuclear factor kappaB pathways. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016] External Links: Ensembl ID: ENSG00000033800 HGNC ID: HGNC:2752 Entrez Gene: 8554

Expression Profile of PIAS1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-300 YES YES NO hsa-miR-34a-5p YES YES NO hsa-miR-34c-5p YES YES NO hsa-miR-375 YES YES YES hsa-miR-377-3p YES YES NO hsa-miR-381-3p YES YES NO hsa-miR-449a YES YES NO hsa-miR-449b-5p YES YES NO hsa-miR-491-5p YES YES NO Display: