Entry Detail



General Information

Database ID:SKCM01902
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:FANCI
Full Name:FA complementation group I
Category:mRNA
Synonyms:KIAA1794
Chromosome:chr15
Strand:+
Coordinate:
Start Site(bp):89243949End Site(bp):89317261
Gene Summary:The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group I. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
External Links:
Ensembl ID:ENSG00000140525
HGNC ID:HGNC:25568
Entrez Gene:55215



Expression Profile of FANCI Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-129-5p
YES
YES
NO
hsa-miR-150-5p
YES
YES
NO
hsa-miR-21-5p
YES
YES
NO
hsa-miR-218-5p
YES
YES
NO
hsa-miR-23a-3p
YES
YES
NO
hsa-miR-23b-3p
YES
YES
NO
hsa-miR-590-5p
YES
YES
NO
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