ctcRbase

Entry Detail

---



General Information

Database ID: SKCM01920 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: PRPS1 Full Name: phosphoribosyl pyrophosphate synthetase 1 Category: mRNA Synonyms: ARTS|CMTX5|DFN2|DFNX1|PPRibP|PRS-I|PRSI Chromosome: chrX Strand: + Coordinate: Start Site(bp): 107628424 End Site(bp): 107651026 Gene Summary: This gene encodes an enzyme that catalyzes the phosphoribosylation of ribose 5-phosphate to 5-phosphoribosyl-1-pyrophosphate, which is necessary for purine metabolism and nucleotide biosynthesis. Defects in this gene are a cause of phosphoribosylpyrophosphate synthetase superactivity, Charcot-Marie-Tooth disease X-linked recessive type 5 and Arts Syndrome. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011] External Links: Ensembl ID: ENSG00000147224 HGNC ID: HGNC:9462 Entrez Gene: 5631

Expression Profile of PRPS1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-124-3p YES YES YES hsa-miR-146a-5p YES YES NO hsa-miR-146b-5p YES YES NO hsa-miR-150-5p YES YES YES hsa-miR-193a-5p YES NO YES hsa-miR-200b-3p YES YES NO hsa-miR-200c-3p YES YES NO hsa-miR-216a-5p YES YES NO hsa-miR-221-3p YES YES NO hsa-miR-222-3p YES YES NO hsa-miR-27a-3p YES YES NO hsa-miR-27b-3p YES YES NO hsa-miR-299-3p YES YES YES hsa-miR-320a YES YES YES hsa-miR-320b YES YES YES hsa-miR-320c YES YES YES hsa-miR-320d YES YES YES hsa-miR-329-3p YES YES NO hsa-miR-335-5p YES YES NO hsa-miR-342-3p YES YES NO hsa-miR-362-3p YES YES NO hsa-miR-376c-3p YES YES NO hsa-miR-377-3p YES YES NO hsa-miR-429 YES YES NO hsa-miR-494-3p YES YES NO hsa-miR-506-3p YES YES NO hsa-miR-7-5p YES YES NO Display: