Entry Detail



General Information

Database ID:SKCM01927
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:PRMT5
Full Name:protein arginine methyltransferase 5
Category:mRNA
Synonyms:HRMT1L5|IBP72|JBP1|SKB1|SKB1Hs
Chromosome:chr14
Strand:-
Coordinate:
Start Site(bp):22920511End Site(bp):22929585
Gene Summary:This gene encodes an enzyme that belongs to the methyltransferase family. The encoded protein catalyzes the transfer of methyl groups to the amino acid arginine, in target proteins that include histones, transcriptional elongation factors and the tumor suppressor p53. This gene plays a role in several cellular processes, including transcriptional regulation, and the assembly of small nuclear ribonucleoproteins. A pseudogene of this gene has been defined on chromosome 4. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2015]
External Links:
Ensembl ID:ENSG00000100462
HGNC ID:HGNC:10894
Entrez Gene:10419



Expression Profile of PRMT5 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:NA
Display:N/A