Entry Detail



General Information

Database ID:SKCM01934
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:UBXN8
Full Name:UBX domain protein 8
Category:mRNA
Synonyms:D8S2298E|REP8|UBXD6
Chromosome:chr8
Strand:+
Coordinate:
Start Site(bp):30732247End Site(bp):30767006
Gene Summary:p97 or VCP (valosin-containing protein) is a versatile ATPase complex, and many cofactors are required for the p97 functional diversity. This gene encodes one of the p97 cofactors. This cofactor is a transmembrane protein and localized in the endoplasmic reticulum (ER) membrane. It tethers p97 to the ER membrane via its UBX domain. The association of this cofactor with p97 facilitates efficient ER-associated degradation of misfolded proteins. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2013]
External Links:
Ensembl ID:ENSG00000104691
HGNC ID:HGNC:30307
Entrez Gene:7993



Expression Profile of UBXN8 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-194-5p
YES
YES
NO
hsa-miR-214-3p
YES
YES
NO
hsa-miR-217
YES
YES
NO
hsa-miR-27a-3p
YES
YES
NO
hsa-miR-27b-3p
YES
YES
NO
hsa-miR-448
YES
YES
NO
hsa-miR-543
YES
YES
NO
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