ctcRbase

Entry Detail

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General Information

Database ID: SKCM01944 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: CETN3 Full Name: centrin 3 Category: mRNA Synonyms: CDC31|CEN3 Chromosome: chr5 Strand: - Coordinate: Start Site(bp): 90392261 End Site(bp): 90409786 Gene Summary: The protein encoded by this gene contains four EF-hand calcium binding domains, and is a member of the centrin protein family. Centrins are evolutionarily conserved proteins similar to the CDC31 protein of S. cerevisiae. Yeast CDC31 is located at the centrosome of interphase and mitotic cells, where it plays a fundamental role in centrosome duplication and separation. Multiple forms of the proteins similar to the yeast centrin have been identified in human and other mammalian cells, some of which have been shown to be associated with centrosome fractions. This protein appears to be one of the most abundant centrins associated with centrosome, which suggests a similar function to its yeast counterpart. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014] External Links: Ensembl ID: ENSG00000153140 HGNC ID: HGNC:1868 Entrez Gene: 1070

Expression Profile of CETN3 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES YES NO hsa-miR-132-3p YES YES NO hsa-miR-133a-3p YES YES YES hsa-miR-133b YES YES YES hsa-miR-134-5p YES YES NO hsa-miR-181a-5p YES YES NO hsa-miR-181b-5p YES YES NO hsa-miR-181c-5p YES YES NO hsa-miR-181d-5p YES YES NO hsa-miR-186-5p YES YES NO hsa-miR-205-5p YES YES NO hsa-miR-212-3p YES YES NO hsa-miR-217 YES YES NO hsa-miR-23a-3p YES YES NO hsa-miR-23b-3p YES YES NO hsa-miR-377-3p YES YES NO hsa-miR-382-5p YES YES NO hsa-miR-410-3p YES YES NO hsa-miR-543 YES YES NO Display: