ctcRbase

Entry Detail

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General Information

Database ID: SKCM01949 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: PPFIA1 Full Name: PTPRF interacting protein alpha 1 Category: mRNA Synonyms: LIP.1|LIP1|LIPRIN Chromosome: chr11 Strand: + Coordinate: Start Site(bp): 70270700 End Site(bp): 70384403 Gene Summary: The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. This protein binds to the intracellular membrane-distal phosphatase domain of tyrosine phosphatase LAR, and appears to localize LAR to cell focal adhesions. This interaction may regulate the disassembly of focal adhesion and thus help orchestrate cell-matrix interactions. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000131626 HGNC ID: HGNC:9245 Entrez Gene: 8500

Expression Profile of PPFIA1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES YES YES hsa-miR-132-3p YES YES NO hsa-miR-135a-5p YES YES NO hsa-miR-135b-5p YES YES NO hsa-miR-144-3p YES YES YES hsa-miR-153-3p YES YES NO hsa-miR-181a-5p YES YES YES hsa-miR-181b-5p YES YES YES hsa-miR-181c-5p YES YES YES hsa-miR-181d-5p YES YES YES hsa-miR-186-5p YES YES NO hsa-miR-200b-3p YES YES YES hsa-miR-200c-3p YES YES YES hsa-miR-212-3p YES YES NO hsa-miR-223-3p YES YES NO hsa-miR-28-5p YES YES NO hsa-miR-300 YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-376a-3p YES YES NO hsa-miR-376b-3p YES YES NO hsa-miR-381-3p YES YES NO hsa-miR-382-5p YES YES NO hsa-miR-410-3p YES YES NO hsa-miR-411-5p YES YES NO hsa-miR-429 YES YES YES hsa-miR-433-3p YES YES NO hsa-miR-448 YES YES NO hsa-miR-488-3p YES YES NO hsa-miR-494-3p YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-543 YES YES NO hsa-miR-708-5p YES YES NO hsa-miR-873-5p YES YES NO hsa-miR-876-5p YES YES NO Display: