Entry Detail



General Information

Database ID:SKCM01961
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:MAGEB1
Full Name:MAGE family member B1
Category:mRNA
Synonyms:CT3.1|DAM10|MAGE-Xp|MAGEL1
Chromosome:chrX
Strand:+
Coordinate:
Start Site(bp):30243730End Site(bp):30252038
Gene Summary:This gene is a member of the MAGEB gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 68% sequence identity to each other. The promoters and first exons of the MAGEB genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. This gene is localized in the DSS (dosage-sensitive sex reversal) critical region, and expressed in testis and in a significant fraction of tumors of various histological types. This gene and other MAGEB members are clustered on chromosome Xp22-p21. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene, however, the full length nature of some variants has not been defined. [provided by RefSeq, Jul 2008]
External Links:
Ensembl ID:ENSG00000214107
HGNC ID:HGNC:6808
Entrez Gene:4112



Expression Profile of MAGEB1 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-181a-5p
YES
YES
NO
hsa-miR-181b-5p
YES
YES
NO
hsa-miR-181c-5p
YES
YES
NO
hsa-miR-181d-5p
YES
YES
NO
hsa-miR-186-5p
YES
YES
NO
hsa-miR-29a-3p
YES
YES
NO
hsa-miR-29b-3p
YES
YES
NO
hsa-miR-29c-3p
YES
YES
NO
hsa-miR-320a
YES
YES
NO
hsa-miR-320b
YES
YES
NO
hsa-miR-320c
YES
YES
NO
hsa-miR-320d
YES
YES
NO
hsa-miR-543
YES
YES
NO
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