ctcRbase

Entry Detail

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General Information

Database ID: SKCM01996 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: EIF5B Full Name: eukaryotic translation initiation factor 5B Category: mRNA Synonyms: IF2 Chromosome: chr2 Strand: + Coordinate: Start Site(bp): 99337353 End Site(bp): 99401326 Gene Summary: Accurate initiation of translation in eukaryotes is complex and requires many factors, some of which are composed of multiple subunits. The process is simpler in prokaryotes which have only three initiation factors (IF1, IF2, IF3). Two of these factors are conserved in eukaryotes: the homolog of IF1 is eIF1A and the homolog of IF2 is eIF5B. This gene encodes eIF5B. Factors eIF1A and eIF5B interact on the ribosome along with other initiation factors and GTP to position the initiation methionine tRNA on the start codon of the mRNA so that translation initiates accurately. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000158417 HGNC ID: HGNC:30793 Entrez Gene: 9669

Expression Profile of EIF5B Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-142-3p YES YES NO hsa-miR-144-3p YES YES NO hsa-miR-145-5p YES YES NO hsa-miR-153-3p YES YES NO hsa-miR-16-5p YES YES NO hsa-miR-186-5p YES YES NO hsa-miR-195-5p YES YES NO hsa-miR-196a-5p YES YES NO hsa-miR-196b-5p YES YES NO hsa-miR-199a-5p YES YES YES hsa-miR-199b-5p YES YES YES hsa-miR-200b-3p YES YES YES hsa-miR-200c-3p YES YES YES hsa-miR-217 YES YES YES hsa-miR-218-5p YES YES NO hsa-miR-296-3p YES YES NO hsa-miR-300 YES YES NO hsa-miR-33a-5p YES YES NO hsa-miR-33b-5p YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-361-5p YES YES NO hsa-miR-365a-3p YES YES NO hsa-miR-377-3p YES YES YES hsa-miR-381-3p YES YES NO hsa-miR-429 YES YES YES hsa-miR-448 YES YES NO hsa-miR-491-5p YES YES YES Display: