ctcRbase

Entry Detail

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General Information

Database ID: SKCM02042 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: THOC3 Full Name: THO complex 3 Category: mRNA Synonyms: THO3|hTREX45 Chromosome: chr5 Strand: - Coordinate: Start Site(bp): 175917873 End Site(bp): 176034680 Gene Summary: This gene encodes a component of the nuclear THO transcription elongation complex, which is part of the larger transcription export (TREX) complex that couples messenger RNA processing and export. In humans, the transcription export complex is recruited to the 5'-end of messenger RNAs in a splicing- and cap-dependent manner. Studies of a related complex in mouse suggest that the metazoan transcription export complex is involved in cell differentiation and development. A pseudogene of this gene has been defined on chromosome 5. [provided by RefSeq, May 2013] External Links: Ensembl ID: ENSG00000051596 HGNC ID: HGNC:19072 Entrez Gene: 84321

Expression Profile of THOC3 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-186-5p YES YES NO hsa-miR-223-3p YES YES NO hsa-miR-224-5p YES YES NO hsa-miR-371a-5p YES YES YES hsa-miR-382-5p YES YES NO hsa-miR-495-3p YES YES NO Display: