ctcRbase

Entry Detail

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General Information

Database ID: SKCM02066 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: MRPS27 Full Name: mitochondrial ribosomal protein S27 Category: mRNA Synonyms: MRP-S27|S27mt Chromosome: chr5 Strand: - Coordinate: Start Site(bp): 72219409 End Site(bp): 72320646 Gene Summary: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that may be a functional partner of the death associated protein 3 (DAP3). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2013] External Links: Ensembl ID: ENSG00000113048 HGNC ID: HGNC:14512 Entrez Gene: 23107

Expression Profile of MRPS27 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-136-5p YES YES NO hsa-miR-138-5p YES YES NO hsa-miR-1-3p YES YES NO hsa-miR-147a YES NO NO hsa-miR-153-3p YES YES NO hsa-miR-155-5p YES YES NO hsa-miR-181a-5p YES YES NO hsa-miR-181b-5p YES YES NO hsa-miR-181c-5p YES YES NO hsa-miR-181d-5p YES YES NO hsa-miR-299-3p YES YES NO hsa-miR-376c-3p YES YES NO hsa-miR-382-5p YES YES NO hsa-miR-455-5p YES YES NO hsa-miR-485-5p YES YES YES hsa-miR-543 YES YES NO hsa-miR-613 YES YES NO hsa-miR-875-5p YES YES NO Display: